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Anti-CrkII Antibody
Catalog #: 102-26528
Mouse Anti-CrkII Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P46108 |
| Gene Id | 1398 |
| Gene Symbols | CRK |
| Protein Name / Synonyms | Adapter molecule crk;Avian sarcoma virus CT10 (v crk) oncogene homolog;CRK;CRK isoform 2;CRK isoform II;CRK_HUMAN;CRKII;FLJ38130;OTTHUMP00000115366;OTTHUMP00000198330;p |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot detection of CrkII in Lncap,A431,MCF7 and HT1080 cell lysates using CrkII mouse mAb (1:1000 diluted).Predicted band size: 34kDa.Observed band size: 34kDa.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.