Anti-CUGBP1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q92879
Gene Id	10658
Gene Symbols	CELF1
Protein Name / Synonyms	CUGBP1 (N-term)
Clonality	Polyclonal
Preparation	This CUGBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CUGBP1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specificity

Predicted Reactivity

Mouse, Rat, Chicken

Other Names

CELF1; BRUNOL2; CUGBP; CUGBP1; NAB50; CUGBP Elav-like family member 1; 50 kDa nuclear polyadenylated RNA-binding protein; Bruno-like protein 2; CUG triplet repeat RNA-binding protein 1; CUG-BP- and ETR-3-like factor 1; Deadenylation factor CUG-BP; Embryo deadenylation element-binding protein homolog; RNA-binding protein BRUNOL-2

NCBI Accession #

NP_001020767.1;NP_001166110.1;NP_001166111.1;NP_006551.1;NP_941989.1

Other Accession #

Q4QQT3; P28659; Q5F3T7; NP_001166110.1; NP_001020767.1; NP_941989.1; NP_001166111.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

52063

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	CUGBP1 Antibody (N-term) (Cat# 102-12270) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CUGBP1 antibody detected the CUGBP1 protein (arrow).
	CUGBP1 Antibody (N-term) (102-12270)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CUGBP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products