Anti-CYP2C9 (N-term) (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P11712
Gene Id	1559
Gene Symbols	CYP2C9
Protein Name / Synonyms	CYP2C9 (N-term) (Ascites)
Clonality	Monoclonal
Preparation	This CYP2C9 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9.
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Specificity

Other Names

CYP2C9; CYP2C10; Cytochrome P450 2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase

NCBI Accession #

NP_000762.2

Other Accession #

NP_000762

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

55628

Recommended Dilutions

WB: 1:100-1600

CYP2C9 Antibody (N-term)(Ascites)(Cat# 102-10386) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CYP2C9 antibody detected the CYP2C9 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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