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Anti-CYTH1 (N-term) Antibody
Catalog #: 102-12361
Rabbit Anti-Human CYTH1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15438 |
| Gene Id | 9267 |
| Gene Symbols | CYTH1 |
| Protein Name / Synonyms | CYTH1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | T Helper Cells, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
CYTH1; D17S811E; PSCD1; Cytohesin-1; PH, SEC7 and coiled-coil domain-containing protein 1; SEC7 homolog B2-1
NCBI Accession #
NP_004753.1;NP_059430.2
Other Accession #
P97694; Q9QX11; NP_004753.1; NP_059430.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46413
Recommended Dilutions
WB: 1:1000
 | CYTH1 Antibody (N-term) (Cat# 102-12361) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CYTH1 antibody detected the CYTH1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.