Anti-DAZ4 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q86SG3
Gene Id	57135
Gene Symbols	DAZ4
Protein Name / Synonyms	DAZ4 (Center)
Clonality	Polyclonal
Preparation	This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Specificity

Other Names

DAZ4; Deleted in azoospermia protein 4

NCBI Accession #

NP_001005375.1;NP_065153.1

Other Accession #

Q9NR90; Q13117; Q9NQZ3; NP_001005375.1; NP_065153.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

64785

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	DAZ4 Antibody (Center) (Cat# 102-11629) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the DAZ4 antibody detected the DAZ4 protein (arrow).
	DAZ4 Antibody (Center) (Cat# 102-11629)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DAZ4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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