Anti-DCD Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P81605
Gene Id	117159
Gene Symbols	DCD
Protein Name / Synonyms	DCD, AIDD, DCD-1, DSEP, HCAP, PIF, dermcidin
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.

Dilutions

WB 1:500 - 1:2000
IF 1:50 - 1:100

Format

Calculated MW

8kDa/11kDa/12kDa

Observed MW

11kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human DCD (NP_444513.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse skin, using DCD antibody (144-07280) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 5s.
Western blot - DCD antibody (144-07280)

Immunofluorescence analysis of MCF-7 cells using DCD antibody (144-07280). Blue: DAPI for nuclear staining.
Immunofluorescence - DCD antibody (144-07280)

Expiration:

12 months from the date of shipment when stored properly.

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