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Anti-Desmoglein 3 / DSG3 Antibody, Sodium Azide Free
Catalog #: 188-11020-SAF
Mouse anti-Human Desmoglein 3 Antibody / DSG3 [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P32926 |
| Gene Id | 1830 |
| Gene Symbols | DSG3,CDHF6 |
| Protein Name / Synonyms | Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) |
| Immunogen | A recombinant human protein corresponding to the extracellular portion of DSG3 was used as the immunogen for the Desmoglein 3 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Western Blotting: 0.5-1ug/ml FACS: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 1-2ug/ml Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
| Domain / Region / Terminus | Cell surface |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
Storage
Store the Desmoglein 3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.