Anti-DHCR24 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q15392
Gene Id	1718
Gene Symbols	DHCR24
Protein Name / Synonyms	DHCR24 (N-term)
Clonality	Polyclonal
Preparation	This DHCR24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids from the N-terminal region of human DHCR24.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Specificity

Predicted Reactivity

Monkey

Other Names

DHCR24; KIAA0018; Delta(24)-sterol reductase; 24-dehydrocholesterol reductase; 3-beta-hydroxysterol delta-24-reductase; Diminuto/dwarf1 homolog; Seladin-1

NCBI Accession #

NP_055577.1

Other Accession #

Q8VCH6; Q60HC5

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

60101

Recommended Dilutions

WB: 1:1000

	Western blot analysis of anti-DHCR24 Antibody (N-term) (Cat#AP2851a) in HepG2 cell line lysates (35ug/lane). DHCR24 (arrow) was detected using the purified Pab.
	Western blot analysis of anti-DHCR24 Antibody (N-term) (Cat#AP2851a) in mouse liver tissue lysates (35ug/lane). DHCR24 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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