Anti-DHPS (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P49366
Gene Id	1725
Gene Symbols	DHPS
Protein Name / Synonyms	DHPS (N-term)
Clonality	Polyclonal
Preparation	This DHPS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human DHPS.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity.

Specificity

Other Names

DHPS; DS; Deoxyhypusine synthase

NCBI Accession #

NP_001193903.1;NP_001921.1;NP_037538.1

Other Accession #

NP_001921.1; NP_037538.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

40971

Recommended Dilutions

WB: 1:1000

DHPS Antibody (N-term) (Cat# 102-13251) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DHPS antibody detected the DHPS protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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