Anti-DIAPH3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NSV4
Gene Id	81624
Gene Symbols	DIAPH3
Protein Name / Synonyms	DIAPH3 (C-term)
Clonality	Polyclonal
Preparation	This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Specificity

Other Names

DIAPH3; DIAP3; Protein diaphanous homolog 3; Diaphanous-related formin-3; MDia2

NCBI Accession #

NP_001035982.1;NP_001245295.1;NP_001245296.1;NP_001245297.1;NP_001245298.1;NP_001245299.1;NP_112194.2

Other Accession #

NP_001035982.1; NP_112194.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

136926

Recommended Dilutions

WB: 1:1000

DIAPH3 Antibody (C-term) (Cat# 102-13054) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DIAPH3 antibody detected the DIAPH3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products