Anti-DLC1 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Mouse, Rat
Host Species	Rabbit
Accession Number	Q96QB1
Gene Id	10395
Gene Symbols	DLC1
Protein Name / Synonyms	DLC1, ARHGAP7, HP, STARD12, p122-RhoGAP, rho GTPase-activating protein 7
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC
Research Area	Apoptosis, Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW

50kDa/54kDa/114kDa/122kDa/126kDa/170kDa

Observed MW

171kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse lung, using DLC1 antibody (144-01921) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Western blot - DLC1 antibody (144-01921)

Immunohistochemistry of paraffin-embedded rat kidney using DLC1 antibody (144-01921) at dilution of 1:200 (40x lens).
Immunohistochemistry - DLC1 antibody (144-01921)

Expiration:

12 months from the date of shipment when stored properly.

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