Anti-DLK Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P80370\|NP_003827.3
Gene Id	8788
Gene Symbols	DLK1
Protein Name / Synonyms	Protein delta homolog 1, DLK-1, pG2, Fetal antigen 1, FA1, DLK1, DLK
Clonality	Polyclonal
Clone	RB15965
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Other Information

NCBI Accession #

NP_003827.3

Antigen Type

Recombinant Protein

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

41300

Antigen Source

Human

Images

WB (1:1000)

DLK Antibody (Cat. #102-20787) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DLK antibody detected the DLK protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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