RayBiotech

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ISO 13485:2016 cGMP

Anti-DMRT1 Antibody

Catalog #: 144-66606

DMRT1 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9Y5R6
Gene Id
1761
Gene Symbols
DMRT1
Protein Name / Synonyms
DMRT1, CT154, DMT1, doublesex and mab-3 related transcription factor 1
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaCancer
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
18kDa/28kDa/39kDa
Observed MW
50kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 134-373 of human DMRT1 (NP_068770.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.