Anti-Dnmt3L Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9CWR8
Gene Id	54427
Gene Symbols	DNMT3L
Protein Name / Synonyms	Dnmt3L
Clonality	Polyclonal
Preparation	This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.

Specificity

Predicted Reactivity

Rat

Other Names

Dnmt3l; DNA (cytosine-5)-methyltransferase 3-like

NCBI Accession #

NP_001075164.1;NP_062321.1

Other Accession #

Q1LZ50

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47993

Recommended Dilutions

WB: 1:1000

	Western blot analysis of Mouse Dnmt3L Antibody (Cat# 102-10722) in Hela cell line lysates (35ug/lane). Dnmt3l (arrow) was detected using the purified Pab.
	Dnmt3l Antibody (C403) (Cat# 102-10722) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dnmt3l antibody detected the Dnmt3l protein (arrow).

Antigen Source

MOUSE

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products