Anti-DR1 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q01658
Gene Id	1810
Gene Symbols	DR1
Protein Name / Synonyms	DR1 (Center)
Clonality	Polyclonal
Preparation	This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-112 amino acids from the Central region of human DR1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Specificity

Predicted Reactivity

Rat, Chicken

Other Names

DR1; Protein Dr1; Down-regulator of transcription 1; Negative cofactor 2-beta; TATA-binding protein-associated phosphoprotein

NCBI Accession #

NP_001929.1

Other Accession #

Q5XI68; Q91WV0; Q5ZMV3; NP_001929.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

19444

Recommended Dilutions

WB: 1:1000

	DR1 Antibody (Center) (Cat# 102-13554) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).
	DR1 Antibody (Center) (Cat# 102-13554) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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