RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

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770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-DRP1 Antibody

Catalog #: 144-64573

DRP1 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
O00429
Gene Id
10059
Gene Symbols
DNM1L
Protein Name / Synonyms
DNM1L, DLP1, DRP1, DVLP, DYMPLE, EMPF, EMPF1, HDYNIV, dynamin 1 like
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.09% Sodium azide, 50% glycerol, pH 7.3
Recommended ApplicationsWestern Blotting, IF
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Dilutions

WB 1:500 - 1:2000; IF 1:50 - 1:200

Format

Calculated MW
60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa
Observed MW
82kDa

Immunogen

Recombinant protein of human DRP1

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.