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Anti-DSG1 (Center) Antibody
Catalog #: 102-12485
Rabbit Anti-Human DSG1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q02413 |
| Gene Id | 1828 |
| Gene Symbols | DSG1 |
| Protein Name / Synonyms | DSG1 (Center) |
| Clonality | Polyclonal |
| Preparation | This DSG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the Central region of human DSG1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Specificity
Other Names
DSG1; CDHF4; Desmoglein-1; Cadherin family member 4; Desmosomal glycoprotein 1; Pemphigus foliaceus antigen
NCBI Accession #
NP_001933.2
Other Accession #
NP_001933.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
113748
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | DSG1 Antibody (Center) (Cat# 102-12485) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DSG1 antibody detected the DSG1 protein (arrow). |
 | DSG1 Antibody (Center) (102-12485)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DSG1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.