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Anti-DUSP2 (C-term) Antibody

Catalog #: 102-18137

Rabbit Anti-DUSP2 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
Q05923
Gene Id
1844
Gene Symbols
DUSP2
Protein Name / Synonyms
DUSP2 (C-term)
ClonalityPolyclonal
PreparationThis DUSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human DUSP2.
Concentration (lot specific)
2.000 mg/ml
Recommended ApplicationsWestern Blotting, FC
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Specificity

Other Names
DUSP2; PAC1; Dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC-1
NCBI Accession #
NP_004409.1
Other Accession #
Q05922

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
34400
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
Western blot analysis of DUSP2 Antibody (C-term) (Cat# 102-18137) in mouse liver tissue lysates (35ug/lane). DUSP2 (arrow) was detected using the purified Pab.
DUSP2 Antibody (C-term) (Cat# 102-18137) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.