Anti-EIF3A (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q14152\|Q1JU68\|P23116\|NP_003741.1
Gene Id	8661
Gene Symbols	EIF3A
Protein Name / Synonyms	Eukaryotic translation initiation factor 3 subunit A {ECO:0000255\|HAMAP-Rule:MF_03000}, eIF3a {ECO:0000255\|HAMAP-Rule:MF_03000}, Eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255\|HAMAP-Rule:MF_03000}, eIF-3-theta {ECO:0000255\|HAMAP-Rule:MF_03000}, eIF3 p167, eIF3 p180, eIF3 p185, EIF3A {ECO:0000255\|HAMAP-Rule:MF_03000}
Clonality	Polyclonal
Clone	RB32052
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Other Information

NCBI Accession #

NP_003741.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

166569

Antigen Source

Human

Images

WB (1:1000)

EIF3A Antibody (C-term) (Cat. #102-21296) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the EIF3A antibody detected the EIF3A protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products