Anti-EIF3CL (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q99613\|B5ME19\|B5DFC8\|Q8R1B4\|Q3SYW6\|NP_001032897.1\|NP_003743.1
Gene Id	8663
Gene Symbols	EIF3C
Protein Name / Synonyms	Eukaryotic translation initiation factor 3 subunit C {ECO:0000255\|HAMAP-Rule:MF_03002}, eIF3c {ECO:0000255\|HAMAP-Rule:MF_03002}, Eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255\|HAMAP-Rule:MF_03002}, eIF3 p110 {ECO:0000255\|HAMAP-Rule:MF_03002}, EIF3C {ECO:0000255\|HAMAP-Rule:MF_03002}
Clonality	Polyclonal
Clone	RB32067
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Other Information

NCBI Accession #

NP_001032897.1;NP_001186071.1;NP_001254503.1;NP_003743.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

105344

Antigen Source

Human

Images

WB (1:1000)

All lanes : Anti-EIF3CL Antibody (N-term) at 1:1000 dilution Lane 1: K562 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 105 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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