Anti-EIF4EBP1 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q13541
Gene Id	1978
Gene Symbols	EIF4EBP1
Protein Name / Synonyms	EIF4EBP1
Clonality	Monoclonal
Preparation	This EIF4EBP1 monoclonal antibody is generated from mouse immunized with EIF4EBP1 recombinant protein.
Concentration (lot specific)	0.260 mg/ml
Recommended Applications	Western Blotting
Research Area	mTOR Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq].

Specificity

Other Names

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1

NCBI Accession #

NP_004086.1

Other Accession #

NP_004086.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

12580

Recommended Dilutions

WB: 1:100-250

EIF4EBP1 Antibody (Cat# 102-10168) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF4EBP1 antibody detected the EIF4EBP1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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