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Anti-ERCC8 (Center) Antibody
Catalog #: 102-10874
Rabbit Anti-ERCC8 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q13216 |
| Gene Id | 1161 |
| Gene Symbols | ERCC8 |
| Protein Name / Synonyms | ERCC8 (Center) |
| Clonality | Polyclonal |
| Preparation | This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Specificity
Other Names
ERCC8; CKN1; CSA; DNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA
NCBI Accession #
NP_000073.1
Other Accession #
NP_000073.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44055
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | ERCC8 Antibody (Center) (Cat# 102-10874) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ERCC8 antibody detected the ERCC8 protein (arrow). |
 | ERCC8 antibody (Center) (Cat# 102-10874) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERCC8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.