3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-EXOSC8 (C-term) Antibody
Catalog #: 102-15139
Rabbit Anti-Human EXOSC8 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96B26 |
| Gene Id | 11340 |
| Gene Symbols | EXOSC8 |
| Protein Name / Synonyms | EXOSC8 (C-term) |
| Clonality | Polyclonal |
| Preparation | This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
Specificity
Other Names
EXOSC8; OIP2; RRP43; Exosome complex component RRP43; Exosome component 8; Opa-interacting protein 2; Ribosomal RNA-processing protein 43; p9
NCBI Accession #
NP_852480.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
30040
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of anti-EXOSC8 Antibody (C-term) (Cat# 102-15139) in HL60 cell line lysates (35ug/lane). EXOSC8(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | EXOSC8 Antibody (C-term) (Cat# 102-15139) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.