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Anti-F2 Antibody
Catalog #: 144-62315
F2 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P00734 |
| Gene Id | 2147 |
| Gene Symbols | F2 |
| Protein Name / Synonyms | F2, PT, RPRGL2, THPH1, prothrombin |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IF |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants.
Dilutions
WB 1:500 - 1:2000; IF 1:50 - 1:200
Format
Calculated MW
70kDa
Observed MW
88kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 75-280 of human F2 (NP_000497.1).
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.