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Anti-FAS (C-terminus) Antibody
Catalog #: 102-26460
Mouse Anti-FAS (C-terminus) Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P25445 |
| Gene Id | 355 |
| Gene Symbols | FAS |
| Protein Name / Synonyms | ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antig |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting |
| Research Area | Apoptosis, Autoimmune Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot detection of FAS(C-terminus) in Jurkat cell lysates using FAS(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 45KDa.Observed band size: 45KDa.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.