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Anti-FCAR (Center) Antibody
Catalog #: 102-11789
Rabbit Anti-Human FCAR (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P24071 |
| Gene Id | 2204 |
| Gene Symbols | FCAR |
| Protein Name / Synonyms | FCAR (Center) |
| Clonality | Polyclonal |
| Preparation | This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Specificity
Other Names
FCAR; CD89; Immunoglobulin alpha Fc receptor; CD_antigen=CD89; Flags: Precursor
NCBI Accession #
NP_001991.1;NP_579803.1;NP_579805.1;NP_579806.1;NP_579807.1;NP_579808.1;NP_579811.1;NP_579812.1;NP_579813.1
Other Accession #
NP_579805.1; NP_579803.1; NP_001991.1; NP_579813.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
32265
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Antibody (Center) (Cat# 102-11789). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.