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Anti-Ferritin Antibody (light chain specific), Sodium Azide Free
Catalog #: 188-11439-SAF
Mouse anti-Human Ferritin Antibody (light chain specific) [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P02792 |
| Gene Id | 2512 |
| Gene Symbols | FTL |
| Protein Name / Synonyms | Ferritin light chain (Ferritin L subunit) |
| Immunogen | Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific). |
| Isotype | IgG2b |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free |
| Recommended Applications | Western blot: 1-2ug/ml FACS: 0.5-1ug/10^6 cells IF: 1-2ug/ml IHC (FFPE): 0.5-1ug/ml for 30 min at RT (1) |
| Domain / Region / Terminus | Cytoplasmic |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Storage
Store the Ferritin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.