Anti-FGF4 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Rat
Host Species	Rabbit
Accession Number	P08620
Gene Id	2249
Gene Symbols	FGF4
Protein Name / Synonyms	FGF4, HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF, fibroblast growth factor 4
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW

12kDa/22kDa

Observed MW

22kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 31-206 of human FGF4 (NP_001998.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of rat liver, using FGF4 antibody (144-60768) at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Western blot - FGF4 antibody (144-60768)

Expiration:

12 months from the date of shipment when stored properly.

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