Anti-FGG Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P02679
Gene Id	2266
Gene Symbols	FGG
Protein Name / Synonyms	FGG, fibrinogen gamma chain
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IF
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Dilutions

WB 1:500 - 1:2000
IF 1:50 - 1:200

Format

Calculated MW

49kDa/51kDa

Observed MW

53kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human FGG (NP_000500.2).

Modification

Unmodified

Storage

-20°C

Images

Immunofluorescence analysis of U-2 OS cells using FGG antibody (144-05642) at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot - FGG Polyclonal Antibody (144-05642)

Immunofluorescence analysis of NIH/3T3 cells using FGG antibody (144-05642) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - FGG Polyclonal Antibody (144-05642)

Expiration:

12 months from the date of shipment when stored properly.

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