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Anti-FOLR2 (N-term) Antibody

Catalog #: 102-12817

Rabbit Anti-Human FOLR2 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P14207
Gene Id
2350
Gene Symbols
FOLR2
Protein Name / Synonyms
FOLR2 (N-term)
ClonalityPolyclonal
PreparationThis FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
Concentration (lot specific)
0.350 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Specificity

Predicted Reactivity
Mouse
Other Names
FOLR2; Folate receptor beta; Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein
NCBI Accession #
NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1
Other Accession #
Q05685; NP_001107008.1; NP_000794.3; NP_001107007.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
29280
Recommended Dilutions
WB: 1:1000
FOLR2 Antibody (N-term) (Cat# 102-12817) western blot analysis in MDA-MB453,NCI-H460 cell line lysates (35ug/lane).This demonstrates the FOLR2 antibody detected the FOLR2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.