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Anti-FOXO3 (Center) Antibody

Catalog #: 102-12345

Rabbit Anti-Human FOXO3 (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O43524
Gene Id
2309
Gene Symbols
FOXO3
Protein Name / Synonyms
FOXO3 (Center)
ClonalityPolyclonal
PreparationThis FOXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human FOXO3.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P, IF
Research AreaCancer, Autophagy
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Specificity

Predicted Reactivity
Mouse
Other Names
FOXO3; FKHRL1; FOXO3A; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
NCBI Accession #
NP_001446.1;NP_963853.1
Other Accession #
Q9WVH4; NP_963853.1; NP_001446.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
71277
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
FOXO3 Antibody (Center) (Cat# 102-12345) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FOXO3 antibody detected the FOXO3 protein (arrow).
FOXO3 Antibody (Center) (Cat# 102-12345)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ANKS1B FOXO3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of FOXO3 Antibody (Center)(Cat# 102-12345) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.