Anti-FOXP2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	O15409
Gene Id	93986
Gene Symbols	FOXP2
Protein Name / Synonyms	FOXP2 (C-term)
Clonality	Polyclonal
Preparation	This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids from the C-terminal region of human FOXP2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Specificity

Predicted Reactivity

Rat

Other Names

FOXP2; CAGH44; TNRC10; Forkhead box protein P2; CAG repeat protein 44; Trinucleotide repeat-containing gene 10 protein

NCBI Accession #

NP_001166237.1;NP_001166238.1;NP_055306.1;NP_683696.2;NP_683697.2;NP_683698.2

Other Accession #

P0CF24; P58463; NP_055306.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

79919

Recommended Dilutions

WB: 1:1000; IF: 1:10-50

	FOXP2 Antibody (C-term) (Cat# 102-16572) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the FOXP2 antibody detected FOXP2 protein (arrow).
	Confocal immunofluorescent analysis of FOXP2 Antibody (C-term)(Cat# 102-16572) with HepG2 cell followed by Alexa Fluor^® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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