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Anti-FXN (C-term) Antibody
Catalog #: 102-16776
Rabbit Anti-Human FXN (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16595 |
| Gene Id | 2395 |
| Gene Symbols | FXN |
| Protein Name / Synonyms | FXN (C-term) |
| Clonality | Polyclonal |
| Preparation | This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the C-terminal region of human FXN. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
Specificity
Predicted Reactivity
Mouse
Other Names
FXN; FRDA; X25; Frataxin, mitochondrial; Friedreich ataxia protein; Frataxin intermediate form; Frataxin(56-210); m56-FXN; Frataxin(78-210); d-FXN; m78-FXN; Frataxin mature form; Frataxin(81-210); m81-FXN
NCBI Accession #
NP_000135.2;NP_001155178.1;NP_852090.1
Other Accession #
O35943
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23135
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-FXN Antibody (C-term) (Cat# 102-16776) in 293 cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab. |
 | Western blot analysis of FXN (arrow) using rabbit polyclonal FXN Antibody (C-term) (RB12571). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN antibody (C-term) (Cat# 102-16776), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.