Anti-FZD7 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O75084
Gene Id	8324
Gene Symbols	FZD7
Protein Name / Synonyms	FZD7 (Center)
Clonality	Polyclonal
Preparation	This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Wnt-beta-Catenin Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Specificity

Predicted Reactivity

Mouse, Chicken

Other Names

FZD7; Frizzled-7; FzE3

NCBI Accession #

NP_003498.1

Other Accession #

Q61090; O57329; NP_003498.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

63620

Recommended Dilutions

WB: 1:1000

FZD7 Antibody (Center) (Cat# 102-13631) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FZD7 antibody detected the FZD7 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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