RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-GAB3 (N-term) Antibody

Catalog #: 102-12972

Rabbit Anti-Human GAB3 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q8WWW8
Gene Id
139716
Gene Symbols
GAB3
Protein Name / Synonyms
GAB3 (N-term)
ClonalityPolyclonal
PreparationThis GAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human GAB3.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names
GAB3; GRB2-associated-binding protein 3; GRB2-associated binder 3; Growth factor receptor bound protein 2-associated protein 3
NCBI Accession #
NP_001075042.1;NP_542179.1
Other Accession #
NP_542179.1; NP_001075042.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
65589
Recommended Dilutions
WB: 1:1000
GAB3 Antibody (N-term) (Cat# 102-12972) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the GAB3 antibody detected the GAB3 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.