Anti-GC (Center) (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P04062
Gene Id	2629
Gene Symbols	GBA
Protein Name / Synonyms	GC(Center) (Ascites)
Clonality	Monoclonal
Preparation	This GC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease, Cancer, Inflammation, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Specificity

Predicted Reactivity

Bovine, Pig

Other Names

GBA; GC; GLUC; Glucosylceramidase; Acid beta-glucosidase; Alglucerase; Beta-glucocerebrosidase; D-glucosyl-N-acylsphingosine glucohydrolase; Imiglucerase

NCBI Accession #

NP_000148.2;NP_001005741.1;NP_001005742.1

Other Accession #

Q70KH2; Q2KHZ8; NP_000148.2

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

59716

Recommended Dilutions

WB: 1:100-1600

GC Antibody(Center) (Cat# 102-10394) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GC antibody detected the GC protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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