Anti-GDF1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P27539
Gene Id	2657
Gene Symbols	GDF1
Protein Name / Synonyms	GDF1 (N-term)
Clonality	Polyclonal
Preparation	This GDF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human GDF1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

GDF1 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right assymetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA which also encodes the longevity assurance gene.

Specificity

Other Names

GDF1; Embryonic growth/differentiation factor 1

NCBI Accession #

NP_001483.3

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39475

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of GDF1 Antibody (N-term) (Cat# 102-14960) in HepG2 cell line lysates (35ug/lane). GDF1 (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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