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Anti-GDF11 (N-term) Antibody

Catalog #: 102-23850

Rabbit Anti-GDF11 (N-term) Antibody, 400 µl

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Specificity
This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.
Host SpeciesRabbit
Accession Number
O95390
Gene Id
10220
Gene Symbols
GDF11
Protein Name / Synonyms
Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11
ClonalityPolyclonal
IsotypeIgG, Rabbit
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

NCBI Accession #
NP_005802.1
Antigen Source
Human
Antigen Type
Synthetic Peptide
Calculated Molecular Weight (Da)
45091
WB (1:2000)

All lanes : Anti-hGDF11-R47 at 1:2000 dilution Lane 1: human heart lysate Lane 2: K562 whole cell lysate Lane 3: mouse kidney lysate Lane 4: 293 whole cell lysate Lane 5: Hela whole cell lysate Lane 5: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

WB
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration
12 months from the date of shipment when stored properly.

Introduction

GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.