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Anti-GDF6 (C-term) Antibody

Catalog #: 102-17382

Rabbit Anti-GDF6 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
Q6KF10
Gene Id
392255
Gene Symbols
GDF6
Protein Name / Synonyms
GDF6 (C-term)
ClonalityPolyclonal
PreparationThis GDF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-353 amino acids from the C-terminal region of human GDF6.
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P, FC
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

GDF6 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this protein result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.

Specificity

Predicted Reactivity
Rat, Bovine
Other Names
GDF6; GDF16; Growth/differentiation factor 6; Growth/differentiation factor 16
NCBI Accession #
NP_001001557.1
Other Accession #
Q6HA10; P43028; P55106

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
50662
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
Western blot analysis of GDF6 antibody (C-term) (Cat# 102-17382) in mouse kidney tissue lysates (35ug/lane). GDF6 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Flow cytometric analysis of 293 cells using GDF6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.