Anti-GLRB (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P48167
Gene Id	2743
Gene Symbols	GLRB
Protein Name / Synonyms	GLRB (N-term)
Clonality	Polyclonal
Preparation	This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

NCBI Accession #

NP_000815.1;NP_001159532.1;NP_001159533.1

Other Accession #

P20781; P48168; Q9GJS9; NP_001159532.1; NP_000815.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

56122

Recommended Dilutions

WB: 1:1000

Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody (N-term)(Cat# 102-12728). 102-12728 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products