Anti-Glucagon Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P01275
Gene Id	2641
Gene Symbols	GCG
Protein Name / Synonyms	Glucagon
Clonality	Monoclonal
Preparation	This Glucagon antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from human Glucagon.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Apoptosis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Specificity

Other Names

GCG; Glucagon; Glicentin; Glicentin-related polypeptide; Oxyntomodulin; Glucagon-like peptide 1; Incretin hormone; Glucagon-like peptide 1(7-37); Glucagon-like peptide 1(7-36); Glucagon-like peptide 2

NCBI Accession #

NP_002045.1

Other Accession #

NP_002045.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

20909

Recommended Dilutions

WB: 1:100-500

Glucagon Antibody (Cat# 102-10170) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the Glucagon antibody detected the Glucagon protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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