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Anti-GR (Phospho-Ser203) Antibody
Catalog #: 102-26374
Rabbit Anti-GR (Phospho-Ser203) Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P04150 |
| Gene Id | 2908 |
| Gene Symbols | NR3C1 |
| Protein Name / Synonyms | Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL |
| Clonality | Polyclonal |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.
Other Information
Antigen Type
synthetic peptide
Images
WB (1:1000)
Western blot analysis of extracts from A549 cells, treated with dexamethason (10 nM, 1 hour), using GR (Phospho-Ser203) antibody.
WB (1:1000)
Western blot analysis of extracts from Hela cells (Lane 2) and Hepg2 cells (Lane 3), using GR (Phospho-Ser203) Antibody. The lane on the left is treated with synthesized peptide.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.