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Anti-Guanylyl Cyclase alpha 1 (GUCY1A3) (N-term) Antibody
Catalog #: 102-17143
Rabbit Anti-Human Guanylyl Cyclase alpha 1 (GUCY1A3) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q02108 |
| Gene Id | 2982 |
| Gene Symbols | GUCY1A3 |
| Protein Name / Synonyms | Guanylyl Cyclase alpha 1 (GUCY1A3) (N-term) |
| Clonality | Polyclonal |
| Preparation | This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3). |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Specificity
Other Names
GUCY1A3; GUC1A3; GUCSA3; GUCY1A1; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit
NCBI Accession #
NP_000847.2;NP_001124154.1;NP_001124155.1;NP_001124156.1;NP_001124159.1;NP_001243378.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
77452
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term) (Cat# 102-17143). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Western blot analysis of anti-GUCY1A3 Pab (Cat# 102-17143) in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.