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ISO 13485:2016 cGMP
Anti-GUCY2F Antibody
Catalog #: 144-60617
GUCY2F Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P51841 |
| Gene Id | 2986 |
| Gene Symbols | GUCY2F |
| Protein Name / Synonyms | GUCY2F, CYGF, GC-F, GUC2DL, GUC2F, RETGC-2, ROS-GC2, retinal guanylyl cyclase 2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
124kDa
Observed MW
125kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of mouse eye, using GUCY2F antibody (144-60617) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Expiration:
12 months from the date of shipment when stored properly.