Anti-H-Ras Antibody

Catalog #: DS-MB-03313

Mouse Anti-Human H-Ras

Product Description

Specifications

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product specifically recognizes human H-Ras, otherwise known as p21Ras, a ubiquitously expressed lipid-anchored GTPase and member of the Ras superfamily of small GTPases, which acts as a molecular signal transduction on/off switch on the inner surface of the plasma membrane and endomembranes. H-Ras, N-Ras and K-Ras4A/4B are highly related RAS genes which regulate pathways involved in cell differentiation, proliferation, adhesion, migration and apoptosis and are known proto-oncogenes. Mutations in the H-Ras gene are responsible for the rare condition known as Costello syndrome characterized by facial, cardiovascular and musculoskeletal abnormalities and mental retardation.
Host Species	Mouse
Protein Name / Synonyms	H-Ras
Concentration (lot specific)	IgG concentration 1.0mg/ml
Recommended Applications	ELISA (dilution: 0.5, 1.0ug/ml), Western Blotting
Research Area	Ras/Rap Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

This product detects a band of approximately 24kDa in HeLa, K567 and RAJI whole cell lysates under reducing conditions.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Synthetic peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras.

Preservative:

0.09% Sodium Azide (NaN₃)

Expiration:

12 months from the date of shipment when stored properly.

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