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Anti-H2AFX (C-term) Antibody
Catalog #: 102-12118
Rabbit Anti-Human H2AFX (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P16104 |
| Gene Id | 3014 |
| Gene Symbols | H2AFX |
| Protein Name / Synonyms | H2AFX (C-term) |
| Clonality | Polyclonal |
| Preparation | This H2AFX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Specificity
Other Names
H2AFX; H2AX; Histone H2A.x
NCBI Accession #
NP_002096.1
Other Accession #
NP_002096.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
15145
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | H2AFX Antibody (C-term) (Cat# 102-12118) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the H2AFX antibody detected the H2AFX protein (arrow). |
 | H2AFX Antibody (C-term) (Cat# 102-12118)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of H2AFX Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.