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Anti-HAT1 (N-term) Antibody

Catalog #: 102-12545

Rabbit Anti-Human HAT1 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O14929
Gene Id
8520
Gene Symbols
HAT1
Protein Name / Synonyms
HAT1 (N-term)
ClonalityPolyclonal
PreparationThis HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HAT1.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Specificity

Predicted Reactivity
Mouse, Rat
Other Names
HAT1; KAT1; Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1
NCBI Accession #
NP_003633.1
Other Accession #
Q5M939; Q8BY71; NP_003633.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49513
Recommended Dilutions
WB: 1:1000
HAT1 Antibody (N-term) (Cat# 102-12545) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HAT1 antibody detected the HAT1 protein (arrow).
Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term) (Cat# 102-12545). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.