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Anti-HBG1 (Center) Antibody
Catalog #: 102-12104
Rabbit Anti-Human HBG1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P69891 |
| Gene Id | 3047 |
| Gene Symbols | HBG1 |
| Protein Name / Synonyms | HBG1 (Center) |
| Clonality | Polyclonal |
| Preparation | This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Specificity
Other Names
HBG1; Hemoglobin subunit gamma-1; Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain
NCBI Accession #
NP_000550.2
Other Accession #
NP_000550.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
16140
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of HBG1 (arrow) using rabbit polyclonal HBG1 Antibody (Center) (Cat# 102-12104). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene. |
 | HBG1 Antibody (Center) (Cat# 102-12104) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HBG1 antibody detected the HBG1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.