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Anti-HCG-beta Antibody, Sodium Azide Free
Catalog #: 188-10063-SAF
Mouse anti-Human HCG-beta Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P0DN86,P0DN87 |
| Gene Id | 1082 |
| Gene Symbols | CGB,CGB3,CGB5,CGB8,CGB7 |
| Protein Name / Synonyms | Choriogonadotropin subunit beta 3 (Choriogonadotropin subunit beta) (CG-beta) (Chorionic gonadotropin chain beta), Choriogonadotropin subunit beta 7 |
| Immunogen | Recombinant protein was used as the immunogen for this HCG-beta antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free |
| Recommended Applications | ELISA: use BSA-free format (1) IHC (FFPE): 0.5-1ug/ml for 30 min at RT (2) Prediluted format: incubate for 30 min at RT (3) |
| Domain / Region / Terminus | Cytoplasmic, Secreted |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This antibody reacts with a protein of 22kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG-beta antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate antibody positivity in 90% and 60% of cases respectively; 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Storage
Store the HCG-beta antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.