Anti-HDAC1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q13547
Gene Id	3065
Gene Symbols	HDAC1
Protein Name / Synonyms	HDAC1 (N-term)
Clonality	Polyclonal
Preparation	This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Specificity

Other Names

HDAC1; RPD3L1; Histone deacetylase 1

NCBI Accession #

NP_004955.2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

55103

Recommended Dilutions

WB: 1:1000; IF: 1:10-50

	HDAC1 Antibody (M1) (Cat# 102-10903) western blot analysis in Hela,K562,mouse NIH/3T3 cell line and mouse testis,rat testis and spleen tissue lysates (35ug/lane).This demonstrates the HDAC1 antibody detected the HDAC1 protein (arrow).
	Confocal immunofluorescent analysis of HDAC1 Antibody (N-term)(Cat# 102-10903) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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